The Leper Chapel in Cambridge has been put on Historic England's "Heritage At Risk" register.
The Chapel of St Mary Magdalene is one of the city's oldest buildings, and was originally the chapel of an isolation hospital caring for people with leprosy.
Over the last 900 years, the site has been a place of worship, a bar and a warehouse, but it now has issues with damp, drainage and cracking masonry.
Owners Cambridge Past, Present & Future, along with Historic England, want to conserve and regularly open this important local landmark for people to enjoy.