The redevelopment of Melbourn Science Park has been given the go ahead.
Staff say the site is "ageing" and needs updating, but some are worried about the size of the new designs.
The developer said the buildings were "no longer fit for purpose" and could fall into decline without work.
Objectors said the new plans, which include a six-storey car park, are "dominating".
Some of the existing buildings are proposed to be kept, but are due to be refurbished and extended.
Record knife amnesty results for Cambridgeshire
A weapons amnesty has seen a record-breaking 370 items handed into police.
Cambridge crowned busiest station in the East
The most and least used railway stations have been revealed with contrasting fortunes in Cambridgeshire.
20mph speed limit approved for Wicken
A 20mph zone has been greenlit for the small village of Wicken near Ely.
Regulators raise "serious" Cambridge Water concerns
Concerns have been raised about water supply in Cambridge and its risk to the environment.
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